Friday, January 28, 2011

Tuesday, January 25, 2011

Assessment Adventures and Anxieties

As a couple of you may already know, I am working in Marsha Linehan’s lab doing clinical assessments for one of her grad students. Marsha Linehan, for those of you who are unfamiliar, combined traditional cognitive behavior therapy with skills training in emotion regulation and mindfulness techniques to create a highly effective therapy for people with Borderline Personality Disorder (BPD) called Dialectical Behavior Therapy (DBT). The study I am assessing for is trying to determine the effectiveness of DBT in treating Axis I disorders (specifically anxiety and depression) in people without BPD. A couple weeks ago, I had the distinct pleasure of doing an assessment on a man (whom we shall call Ted) who has complete Agenesis of the Corpus Callosum (ACC). This means, ladies and gents, that he was born completely without a corpus callosum. Woah. Curious as to how this would affect his behavior, I did a little research before seeing him. With regards to emotion, it seems that people with ACC have difficulties in processing faces, and as a result, frequently get misdiagnosed with Asperger’s or Autism. Also common are cognitive and motor disabilities.


Based on what I had read about ACC, I was expecting to meet someone who was visibly and/or obviously disabled in some way. I was surprised to find that I was shaking hands with a seemingly normal, albeit slightly awkward man. I was even more surprised to find, as the interview commenced, that Ted turned out to be one of most self-aware clients I’ve observed thus far. He knew exactly what his faults and inconsistencies were and had no trouble answering questions about his emotions and behaviors very precisely (typical borderline patients have poor insight into which emotions they're feeling and even poorer control over them). He discussed his “temper tantrums” at length, which had even gotten him arrested on domestic violence charges. He attributed these anger outbursts in part to his inability to recognize emotions in faces, telling me that he flat-out fails tests of facial emotion recognition. He has effectively had to actively learn the skills that most of us were born knowing intuitively—the ability to know that a smile signifies happiness or that a furrowed brow indicates concern. Ted had an uncanny ability to go over a situation in hindsight, but in the emotion-laden moment could not muster his intellectual knowledge of facial emotions enough to put it to use.


Ted also spoke of thinking completely in binaries, saying quite humorously that to him, a grey area is really just more black and white. Though he can barely add and subtract (he claims that an inability to do math is a commonality among people with ACC), he managed to struggle through enough math classes to allow him to become a computer programmer (where he can safely and happily think in binaries). Unfortunately, he met criteria for BPD and so did not qualify for the study I'm assessing for, despite the fact that the treatment seems perfect for him.


It bothered me quite a bit to have to diagnose this client with a personality disorder. Ted has an identifiable structural deficiency in his brain, so why is he being diagnosed with a disorder that uses a behavioral diagnosis and has nothing to say about the underlying biological mechanisms? This seems to be a problem with many DSM diagnostic criteria, in that a single diagnosis can be explained by a multitude of social and biological mechanisms. Is there a difference, then, between someone like Ted, with whom you can point on a brain scan to the root of his emotional difficulties, and someone who has suffered through childhood sexual abuse (typical of borderline patients) and as a result has developed problematic emotional regulation skills? Should we look at these two types of cases differently in terms of diagnosis? What about treatment?

Friday, January 7, 2011

Facial Affective Reactivity in Depression

Taken from "Patterns of Facial Affective Reactivity in Depression: A literature review of emotion elicitation using film" by Jeff Girard (in press).

Clinicians have long relied on nonverbal communication to aid in the diagnosis and assessment of psychopathological populations. Specifically, blunted or flattened displays of facial affect have long been associated with schizophrenia and depression (Marsden et al. 1975). These ratings are usually made subjectively, however, and there are many conflicting theories about how such populations respond to different types of emotion elicitation. Only careful research can properly determine what (if any) patterns of emotion reactivity can be associated with different disorders. This article will review the literature on a subset of this research. Specifically, it will focus on how patients suffering from Major Depressive Disorder differ from healthy controls in terms of facial affect when positive and negative emotions are elicited using film. Although there are many methods for eliciting emotion, film is the focus of this review because it is more naturalistic than asking participants to pose facial expressions, more immersive and engaging than pictorial stimuli, and allows for more experimental control and standardization than emotional imaginings or interviews (Gross & Levenson, 1995).

Four hypotheses about the effect of Major Depressive Disorder (MDD) on facial affective reactivity have been put forth in the literature: positive attenuation (less reactivity to positive stimuli), negative potentiation (more reactivity to negative stimuli), emotion context insensitivity (less reactivity to both positive and negative stimuli), and cultural norm violation (reactivity opposite of cultural expectancy). There is strong evidence from a variety of measures in support of the Positive Attenuation Hypothesis. However, there is no evidence in support of the Negative Potentiation Hypothesis and only tentative support for the Emotion Context Insensitivity and Cultural Norm Hypotheses. More research is needed before definite conclusions can be drawn about the role of cultural norms. Reactivity to positive emotion elicitation was found to be a good indicator of prospective functioning, whereas reactivity to negative emotion elicitation was found to be a good indicator of current psychosocial functioning.


Measure

Article

Positive Attenuation

Negative Potentiation

Emotion-Context Insensitivity

Cultural Norm

Electromyography

(Facial EMG)

Sakamoto et al. 1997

Yes*

-

-

No*

Kaviani et al. 2004

No

No

No

-

Rottenberg et al. 2005

Yes*

No

No

-

Emotion Facial Action Coding System (EMFACS)

Berenbaum et al. 1992

Yes*

No

No

-

Tsai et al. 2003

Yes*

No

No

Yes*

Renneberg et al. 2005

Yes*

No*

Yes*

-

Reed et al. 2007

Yes*

-

-

-

Emotional Expressive Behavior Coding System (EEB)

Rottenberg et al. 2002

No

No

No

-

Chentsova-Dutton et al. 2007

No

No

No

Yes*

Chentsova-Dutton et al. 2010

Yes*

-

-

Yes*

Computer-Based Facial Action Analysis

Schneider et al. 1990

No

No

No

-

Mergl et al. 2005

Yes*

-

-

-

We Are Half Awake


The title for this blog is borrowed from the great William James, a philosopher and one of the first American psychologists. The full quote reads, "Compared to what we ought to be, we are half awake." It is a nice quote in that it captures James' perspective on human nature, something that psychologists are inherently interested in. This blog will hopefully be a place in which we can discuss fun and interesting things such as this and other enigmatic or scientific psychological issues. Enjoy!